Structural and functional determinants of protein kinase CK2α
نویسندگان
چکیده
منابع مشابه
Catalytic activity of mutants of yeast protein kinase CK2α
Yeast CK2 is a highly conserved member of the protein kinase CGMC subfamily composed of two catalytic (α and α′) and two regulatory (β and β′) subunits. The amino-acid sequences of both catalytic subunits are only 60% homologous. Modelling of the tertiary structure of the CK2α displays additional α-helical structures not present in the CK2α′ subunit, connecting the ATPbinding loop with the cata...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography
سال: 2011
ISSN: 0108-7673
DOI: 10.1107/s0108767311092191